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Tātai Hanganga
Raraunga Haumaru
whānui
Taupānga
Ko te waikawa Retinoic (tretinoin) he huaora A huaora.Kua whakaatuhia he kaha ki te whakarereke i te whakahiato collagen, te whakanui ake i nga taumata waikawa hyaluronic dermal, me te whakaongaonga i te tipu fibroblast me te matrix extracellular.Ka whakamahia mo nga mate keratinization me te rongoa i te hakihaki.
Ko te Huaora A, me te tauira ngota C20H28O2, he hua takawaenga o te huaora A i roto i te tinana, e pa ana ki te tipu o te wheua me te whakatairanga i nga paanga o te tipu o te epithelial cell proliferation, te rereketanga me te keratinolysis.Ka whakamahia mo te maimoatanga o te hakihaki vulgaris, psoriasis, ichthyosis, lichen planus, furunculosis whero makawe, keratosis follicular, carcinoma pūtau squamous me te melanoma.
Kāwai: He rerekee te keratinization anti-kiri, he maataki rerekee whakaawe i nga pūtau
Nga tikanga rokiroki: marama-tohu me te hiri
Ko te waikawa Retinoic kaore he paanga ki te mahi tyrosinase me te hanganga melanin o nga melanocytes noa o te tangata.I te wa ka paheke te kiri o te tinana, ka pakaruhia ranei e nga raau taero, te hihi UV, te whara ranei, ka whakatika, ka aukati ranei te waikawa retinoic i nga mea rereke i roto i te hanganga matū koiora me te hanganga morphological o te kiko hono kiri na nga mea kino.Karekau he painga o te waikawa Retinoic ki te whakahiatotanga collagen kiri.I tua atu, ko te waikawa retinoic he mahi aukati i runga i te chemotaxis leukocyte, na reira ka mahi hei kaihoko anti-inflammatory.Ko te waikawa Retinoic karekau he paanga tika ki nga repe sebaceous me o raatau hunanga.